Comparison and Validation of IS900-Sequence and Putative Sequences as Specific Target to Detect Mycobacterium avium subsp. paratuberculosis

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Comparison and Validation of IS900-Sequence andPutative Sequences as a Specific Target to DetectMycobacterium avium subsp. Paratuberculosis

1Department of Pathobiology, College of Veterinary Medicine, Nursing & Allied Health, Tuskegee University, Analysis, Tuskegee, Alabama, USA 2Pharmaceutical Sciences, Mercer University Atlanta Campus, Atlanta, Georgia, USA 3Thompson-Bishop-Sparks State Diagnostic Laboratory, Auburn, Alabama, USA 4Department of Animal Sciences, Auburn University, Auburn, Alabama, USA 5Center for Computational Epi...

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Differential responses of bovine macrophages to Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium.

Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium are antigenically and genetically similar organisms; however, they differ in their virulence for cattle. M. avium subsp. paratuberculosis causes a chronic intestinal infection leading to a chronic wasting disease termed paratuberculosis or Johne's disease, whereas M. avium subsp. avium causes only a transient infec...

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Characterization of IS900 loci in mycobacterium avium subsp. paratuberculosis and development of multiplex PCR typing

Mycobacterium avium subsp. paratuberculosis is a pathogen that causes chronic inflammation of the intestine in many animals, including primates, and is implicated in Crohn's disease in humans. It differs from other members of the M. avium complex in having 14-18 copies of IS900 inserted into conserved loci in its genome. In the present study, genomic DNA flanking 14 of these insertions was char...

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What is Mycobacterium avium subsp. paratuberculosis?

We read with interest the article by Beumer et al. (1) on the detection of Mycobacterium avium subsp. paratuberculosis in 81% of drinking water and biofilm samples by PCR. Although these findings could have a significant influence on our understanding and the potential public impact of M. avium subsp. paratuberculosis as an agent of disease, much of the information on M. avium subsp. paratuberc...

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Mycobacterium avium subsp. paratuberculosis in Veterinary Medicine.

Mycobacterium avium subsp. paratuberculosis (basonym M. paratuberculosis) is the etiologic agent of a severe gastroenteritis in ruminants known as Johne's disease. Economic losses to the cattle industry in the United States are staggering, reaching $1.5 billion annually. A potential pathogenic role in humans in the etiology of Crohn's disease is under investigation. In this article, we review t...

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ژورنال

عنوان ژورنال: Journal of Animal Science and Research

سال: 2017

ISSN: 2576-6457

DOI: 10.16966/2576-6457.101